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Sofosbuvir with daclatasvir and the outcomes of patients with COVID-19: a systematic review and meta-analysis with GRADE assessment

(C) The forest plot of meta-analysis of the association between CRC susceptibility and intake of folate among the MTHFR 677CC + CT genotype

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doi:10.1093/ajcn/81.5.1026

Remarkably, blocking ALDH2, a mitochondrial aldehyde dehydrogenase that can metabolize FA and AA, also induces the signal of FAsor, suggesting that ALDH2 operates to limit the concentration of endogenous FA