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According to the World Health Organization (WHO), in 2000, brain diseases such as Alzheimers disease and other dementias ranked 14th among the causes of death worldwide with approximately 0.8 million deceased [1]

The PPAR/AKT/GPX4 pathway inhibits neuronal ferroptosis, preserves the blood-brain barrier, and promotes myelin regeneration (Bai et al., 2023)

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Biol Trace Elem Res 188:384392 Naghii MR, Mofid M, Asgari AR et al (2011) Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines