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To specifically improve the density for the dynamic TM1a region in the inward-open states, we applied focused 3D classification centered on this helix, followed by non-uniform and local refinement

improper technique increases the risk of nerve injury, infection, or dosing errors

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There were a few cases of headache, dizziness, and fever [51]

Tyr93 inserts into a deep pocket lined by RBD residues Val341, Ala344, Phe347 and Ser399, and buries 143.4 2 of the surface area