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Tissue distribution of labelled material in vitamin C-deficient guinea pigs after intravenous injection of 1- 14 C) ascorbic acid or (1- 14 C) dehydroascorbic acid

Ludmann P

Y-BL: Data curation, Methodology, Writing original draft

In response to ischemia, a sharp increase in the level of HSP70 is recorded, while its highest concentration is observed in vital parts of cells: nuclear, perinuclear space, mitochondria, and endoplasmic reticulum, which indicates the importance of chaperone 70 in protection against death (Sharp et al., 2013)

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The remaining missing data were subjected to kNN imputation, as this method has been proven to provide better performance, robustness, and an overall marginal type 1 error rate [30, 31], especially when the proportion of missing data across samples for a molecular feature is relatively low (as in our datasets, with only 11.6% of imputable variables)