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Lysosomal dysfunction in -synuclein pathology: Molecular mechanisms and therapeutic strategies

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Martinos Center for Biomedical Imaging, Massachusetts General Hospital Radiology, Fujian Medical University Union Hospital Radiology, Harvard Medical School Radiology, Leiden University Medical Center Radiology, Sichuan Provincial People's Hospital RADIOLOGY-Planning Radiolonet Tokai Rady Children's Hospital San Diego Rady Children's Hospital-San Diego, Heart Institute Ramathibodi Hospital Random W Random Walk Imaging Rapid Biomedical GmbH, Rimpar, Germany Reichman University Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University Ren ji Hospital, School of Medicine, Shanghai Jiaotong University Renaissance School of Medicine Renaissance School of Medicine at Stony Brook University Renji hospital Renji Hospital affiliated to Shanghai Jiao Tong University Renji Hospital, School of Medicine, Shanghai Jiao Tong University Renji Hospital, School of Medicine, Shanghai Jiaotong University Renji Hospital, Shanghai Jiao Tong University School of Medicine Renji Hospital, Shanghai Jiao Tong University, School of Medicine Renji Hospital, Shanghai Jiaotong University School of Medicine Renji Hospital,Shanghai Jiao Tong University School of Medicine Renmin Hospital of Wuhan University Renmin University of China Research and Development Laboratory Research and Laboratories Sector, Saudi Food and Drug Authority, Riyadh, KSA Research Campus STIMULATE Research Campus STIMULATE, Otto-von-Guericke University Research Center for Brain-inspired Intelligence Institute of Automation, Chinese Acad Research Center for Brain-inspired Intelligence, Institute of Automation, Chinese Academy of Sciences Research Center of Translational Medicine, Research Centre for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen, C Research Centre Juelich Research Institute for Brain and Blood Vessels Akita Resonance Research Inc

In SRS, there is a normal postnatal expression of the IGF2 gene in the liver leading to normal levels of circulating IGF-II