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In ME/CFS and Long COVID, research suggests that the mitochondria are damaged by chronic oxidative stress and fail to produce ATP efficiently

doi: 10.1080/07853890.2023.2290213 224

138(Pt 7)18011816

Sci Rep 15:3248

It is a progressive condition

172,173 In support of these findings, in vivo studies using mouse stroke models have demonstrated that ATX knockout reduces LPA levels, improves vascular permeability, enhances cerebral blood flow, and decreases infarct volume, collectively reducing HCM-associated vascular dysfunction