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Administration of amino acids to complex I or complex II mutant worms revealed that complex I activity is required for complete serine- and histidine-mediated life extension, while complex II activity is required for proline-mediated life extension (Edwards et al., 2015)

However, in G6PD-deficient cells, the ability to activate any NF-B-mediated immune response is impaired due to an imbalance in reduction and oxidation mechanisms (Fig

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PMID 12814916

Mechanical stress and impingement can generate reactive oxygen species (ROS), which are chemically reactive molecules containing oxygen

10.1002/1873-3468.13631 222 WangH.LiuC.ZhaoY.ZhangW.XuK.LiD.et al (2020a)