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SKU: 61642487877
Price: 29.09 USD
Availability: InStock
Rating: 4.2853 (21 reviews)

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10.16910/jemr.13.4.6 164 Zayas-GarciaS.Cano-de-la-CuerdaR

In the nucleus, receptor dimers bind to androgen response elements (AREs) in the promoter regions of target genes, such as prostate-specific antigen (PSA) and transmembrane protease serine 2 (TMPRSS2), etc , to which they recruit various coregulatory proteins to facilitate transcription, leading to responses such as growth and survival 7,8,9,10,11,12

Consistent with this, recent evidence demonstrates that sulforaphane treatment ameliorates core autism-like behaviors, which are correlated with increased Nrf2 expression, subsequent upregulation of downstream antioxidants, and a concomitant reduction in oxidative stress markers [48, 49, 54]