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Pregnant or nursing women should not use either compound

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On case by case basis, some insurance companies do reimburse for Hormone Replacement Therapy and Testosterone Replacement Therapy

The body readily converts cyanocobalamin to active forms through normal metabolic pathways, so bioavailability differences between B12 forms are minimal in individuals with intact conversion capacity

Crohns is an inflammatory disease that can cause ulcerations throughout the GI tract, specifically affecting the small bowel and colon

Of course, people with a proper vitamin B12 deficiency will see more of a benefit, like improvement with less fatigue, nausea, and irritability