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The systemic inflammatory response generated by the production of cytokines and chemokines during intestinal I/R injury might profoundly disrupt the bloodbrain barrier (BBB) (Guo et al., 2025)

In a rat model of ISO-mediated myocardial infarction, CoQ10 preconditioning not only markedly expanded cardiac GSH levels and reduced the concentration of lipid peroxidation but also alleviated myocardial damage [177]