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However, in recent years, the prevalence of HFpEF has surged, now equaling that of HFrEF, and has become a critical area within the field of heart failure that requires urgent attention[3]

Ranasinghe SL, Fischer K, Zhang W, Gobert GN, McManus DP

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A Phase 2, Randomized, Double-Blind, Vehicle-Controlled, Split-Wound Study of Topical GHK-Cu (Copper(II)-Peptide Complex) Gel to Accelerate Re-Epithelialization of Standardized Acute Skin Wounds in Healthy Adults

Additionally, the development of pharmacological agents that precisely modulate intracellular iron homeostasis, such as iron chelators or iron oxide NPs, or enhance iron bioavailability specifically within the TME, may facilitate the targeted exploitation of ferroptosis pathways

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