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10.1186/s40104-022-00809-w 33 LiangY.HanY.XiaoL.SuY.BaoT.JiX.et al (2025)

i-j , Fluorescence histograms of FSP1 GFP-P2A-BFP cells grown in normal or vitamin B2-deficient medium for 72 h showing changes in GFP:BFP ratio ( i ) or GFP and BFP fluorescence ( j )

The authors declare that they did not receive any funds from any funding agency

4.1.1 Local delivery of RNA-LNPs A straightforward way to bypass hepatic accumulation of LNPs is to change the administration route from intravenous delivery to other administration routes, which could shorten the delivery path and enhance accessibility to the target cells (Figure 3) (Chenthamara et al., 2019