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Camporeale A, Poli V

This elevation in enzyme activity enhances the livers antioxidant defense mechanisms, thereby contributing to the reduction of liver damage (Tung et al., 2009)

Proc Natl Acad Sci U S A 109: 55415546

Oxidative stress is a significant pathologic factor in DMD

These results open therapeutic avenues and prompt the development of future immunotherapy clinical trials combining p300 inhibition with ICT in RMC and potentially other aggressive diseases that may hyperprogress via myeloid mimicry