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The drugs were found to be still good after that period

Lack of historical evidence to support folic acid exacerbation of the neuropathy caused by vitamin B12 deficiency

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Important safety considerations: Patients should call 999 or go to A&E immediately if they experience symptoms of severe allergic reaction such as difficulty breathing, significant swelling of the face or throat, or chest tightness

Many patients notice changes within days to a few weeks, depending on how deficient they were and how consistent the protocol is