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SKU: 60872107595 · From condeoeiras.edu.pt

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The development partners are currently reviewing the Complete Response Letter to better determine the appropriate next steps for GA Depot and continue to believe in its potential as an important new treatment advancement for patients with multiple sclerosis, according to the announcement

doi:10.1177/000456329503200514 [45] Morinet F, Leruez-Ville M, Pillet S, Fichelson S

Fe 2+ overload, ROS accumulation, GSH depletion, LPO, and mitochondrion shrinkage were observed in HSV-1-infected cultured human astrocytes, microglia and murine brains, which are hallmarks of ferroptosis (Xu et al., 2023).The ways of ferroptosis induced by HSV are related to Nrf2, GSH-GPX4 and dihydroorotate dehydrogenase-dihydroubiquione (DHODH-CoQH2) (Mao et al., 2021