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Subsequently, samples were concentrated to dryness in vacuum before dissolving in 150 L of 80% methanol (precooled at -20C), then centrifuged again at 13 500 g and 4C for 10 min to obtain the supernatant for high-performance liquid chromatography Ultimate 3000 (Thermo Fisher Scientific, USA)-tandem mass spectrometry Q Exactive Focus (Thermo Fisher Scientific, USA) (LC-MS/MS) analysis (95, 96)

The establishment of the chronology of A pathology in AD suggests that an inside out hypothesis is likely (Gouras et al., 2014), and we suggest that this supports the interpretation that A pathology is from intraneuronal infection via neurophilic pathogens

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Loss of p53 expression reinforced HGF/c-Met signaling, which promoted invasion and metastasis by upregulating Snail expression (Liu et al., 2016)

Even when chest pain seems noncardiac, certain symptoms always require immediate evaluation

J Vet Med A Physiol Pathol Clin Med 54, 599-606