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This suggests its metabolic influence is primarily on fat oxidation rather than muscle catabolism

Is interleukin-1 a culprit in macrophage-adipocyte crosstalk in obesity

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Deleted in breast cancer 1 plays a functional role in adipocyte differentiation

It binds to incretin receptors in the hypothalamus and gastrointestinal tract, reducing appetite signaling while simultaneously slowing gastric emptying