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10.1016/j.jpba.2017.05.010 46 RizzutiA.AlvarengaC.StockerG.FragaL.SantosH

Generalized: Anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (see WARNINGS)

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To demystify this, consider NAD+ as the fuel for your cellular engines, while 5-Amino-1MQ acts as a mechanic that prevents wasteful leaks, ensuring the fuel lasts longer and works more efficiently

In laboratory testing, it did not inhibit related SAM-dependent methyltransferases or interfere with other enzymes in NAD+ salvage pathways

Secondary objectives Measure whether daily maternal administration of 50 g vitamin B 12 from early pregnancy until 6 months postpartum improves haemoglobin concentration of the mother and infant, and also assess the relationship between maternal and infant haemoglobin concentration on cognitive outcomes at 6 and 12 months of age