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Upregulating cellular motility: Peptides like TB4 (TB-500) alter the cellular cytoskeleton, affecting cells' ability to move and change shape

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In the Xenopus oocyte expression system, examination of rKOR regulation on the activation of potassium channels revealed that over-expression of GRK3 or 5 alone did not promote a significant desensitization which requires both GRK and arrestin 3 (Appleyard et al., 2002)