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200 Enzyme-catalyzed reactions that generate ROS include those involving NADPH oxidase, xanthine oxidase, uncoupled endothelial nitric oxide synthase (eNOS), arachidonic acid and metabolic enzymes such as the cytochrome P450 enzymes, lipoxygenase and cyclooxygenase

doi:10.1210/en.2008-1638

Pathophysiology of Dercum Disease The pathophysiology of Dercum disease needs to be determined by type, something that very few papers have done so accurately

L., Roberts, M

Without catalase, excess H 2 O 2 generated by SOD can react with metal ions, leading to the formation of the highly destructive hydroxyl radical

Keratosis pilaris was reported in 80% (49/61) of participants, a significantly higher frequency than the reported population average of 34% (p=0.018) 18