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gabP Physiological significance of the operon [edit] The gabT gene encodes for GABA transaminase, an enzyme that catalyzes the conversion of GABA and 2-oxoglutarate into succinate semialdehyde and glutamate

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Conversely, interventions that restore TST activity, such as sodium thiosulfate treatment or TST overexpression, significantly alleviate renal tubular injury under high-glucose conditions [130]

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These studies are summarized below

Reference Minich, Deanna M, and Benjamin I Brown