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This anabolic program is regulated by specialized transcription factors, the sterol regulatory element-binding proteins (SREBP) (125)

This possibility becomes especially important when considering vitamin replacement therapy

For decades, studies focused on the synaptic or neuronal level to understand the mechanism of neurological or neurodegenerative disease

Depleted levels of glutathione are recognized to result in susceptibility to cellular deterioration, as a result of multiple circumstances, including oxidative stress, free radical exposure, infections, and toxins.*

Harris BE, Song R, Soong SJ, Diasio RB (1990) Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion

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