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Although it does not have the muscle building or stimulant-like effects of many commonly recognised performance-enhancing drugs, trimetazidine may enhance athletes physical efficiency and endurance

2408-C LINAFEXOR: A PULSE FXR LIGAND THAT FITS METABOLIC CYCLE OF BILE ACIDS TO TREAT NASH Huaqiang Eric Xu, Simm

Nos: 5,292,736, 5,688,825, 5,554,789, 5,455,230, 5,292,736, 5,298,522, 5,216, 165, 5,438,064, 5,204,365, 5,017,578, 4,906,655, 4,906,655, 4,994,450, 4,749,792, 4,980,365, 4,794,110, 4,670,541, 4,737,493, 4,622,326, 4,536,512, 4,719,231, 4,533,671, 4,552,866, 4,539,312, 4,569,942, 4,681,879, 4,511,724, 4,556,672, 4,721 ,712, 4,474,806, 4,595,686, 4,440,779, 4,434,175, 4,608,374, 4,395,402, 4,400,534, 4,374,139, 4,361,583, 4,252,816, 4,251,530, 5,874,459, 5,688,825, 5,554,789, 5,455,230, 5,438,064, 5,298,522, 5,216,165, 5,204,365, 5,030,639, 5,017,578, 5,008,264, 4,994,450, 4,980,365, 4,906,655, 4,847,290, 4,844,907, 4,794,110, 4,791 , 129, 4,774,256, 4,749,792, 4,737,493, 4,721 ,712, 4,719,231 , 4,681 ,879, 4,670,541, 4,667,039, 4,658,037, 4,634,708, 4,623,648, 4,622,326, 4,608,374, 4,595,686, 4,594,188, 4,569,942, 4,556,672, 4,552,866, 4,539,312, 4,536,512, 4,533,671, 4,511,724, 4,440,779, 4,434,175, 4,400,534, 4,395,402, 4,391,827, 4,374, 139, 4,361 ,583, 4,322,420, 4,306,097, 4,252,816, 4,251 ,530, 4,244,955, 4,232,018, 4,209,520, 4,164,514, 4,147,872, 4,133,819, 4,124,713, 4,117,012, 4,064,272, 4,022,836, 3,966,944

Its small molecular weight (~390 Da) supports cellular uptake and is reported to enable direct DNA / chromatin interaction at gene promoter regions, consistent with the broader Khavinson bioregulator hypothesis

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