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doi: 10.1038/s41577-022-00684-6 146 TaoS.DuanR.XuT.HongJ.GuW.LinA.et al

[2] This is the highest tier of evidence in this entire comparison: randomized, blinded, placebo-controlled, with a hard imaging endpoint (visceral fat measured by CT), replicated across two trials, and reviewed by a regulator