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Causes and consequences of impaired methionine synthase activity in acquired and inherited disorders of vitamin B12

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It was observed that the treatment of rats on a high-fat diet with exendin-4 resulted in a decrease in the number of osteoclasts and the area of eroded surfaces, while there was an increase in the osteoid area, bone mass, and trabecular bone volume

Preliminary data from animal studies evaluating the weight-loss benefit of T-BVT, a new 11-HSD1 pharmacological inhibitor with specificity for WAT, are very promising regarding its anti-obesity effectiveness and amelioration of multiple metabolic syndrome parameters (220)