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Key pathways discussed include the RTK, EGFR, and RAS metabolic dependency pathways, as well as metabolic abnormalities arising from IDH mutations

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[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Kanlaya R., Singhto N., Thongboonkerd V

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The pathophysiology of AD is intricate, involving abnormal phosphorylation of Tau protein, neuroinflammation, mitochondrial dysfunction, ferroptosis, and damage to cholinergic neurons