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This deficiency worsens oxidative stress and contributes to complications, including symptoms like fatigue

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These parts represent other important molecules and processes in your body, such as methylation and the system that recycles NAD+ (called the salvage pathway)

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For example, T cell activation upregulates a variety of amino acid transporters, including SLC7A5, and deletion of SLC7A5 leads to activation of the mTOR signaling pathway and upregulation of the transcription factor MYC to inhibit T cell proliferation

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