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Future works searching for genetic and post-translational modifications affecting FLNA expression and function, as well as for a possible involvement of other cytoskeleton proteins, might help to clarify the complex mechanisms involved in pituitary tumors pharmacological resistance

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Oncogene 27(52):66796689

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Research has identified that doses exceeding 0.75g/kg body weight (approximately 51g for a 150-pound individual) may elevate blood ammonia levels, potentially causing toxicity symptoms

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