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A study published in The Lancet Global Health in 2023 estimated the macroeconomic burden of COPD in 204 countries and regions from 2020 to 2050, predicting a global economic loss of $4.326 trillion due to COPD, with China bearing the highest burden at $1.363 trillion [5]

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Smoking increases the risk for development of the metabolic syndrome and its attendant cardiovascular consequences (Chiolero et al., 2008)

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