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Curcumin was also discovered to inhibit the activities of cytochrome P450, glutathione S-transferase, UDP-glucuronosyltransferase, and chelate iron, which has an impact on how it is metabolized throughout the body

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Furthermore, the present data emphasize the interaction between TRAIL-mediated signaling and oxidative stress response, with previous studies demonstrating that ROS production enhances DR5 expression in human carcinoma cell lines (41-43)

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