The sgRNAs were prepared as in the SpCas9 mRNA preparation, except that: a) the gRNA Cloning Vector (Addgene, #41824, ref
SP3-FAIMS chemoproteomics for high-coverage profiling of the human cysteinome
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This formulation combines four peptides that have been studied in preclinical models for their roles in tissue repair processes
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Disclosures: Philip Hemken: Nothing to Disclose, Lori Sokoll: Nothing to Disclose, Laurel Jackson: Abbott Laboratories: Employee, Susan Gawel: Nothing to Disclose, Toru Yoshimura: Abbott Japan: Employee, Abbott Laboratories: Stock - publicly traded company, Hideki Kinukawa: Nothing to Disclose, Shaohua Ning: Nothing to Disclose, Juru Miao: Nothing to Disclose, Daniel Chan: Nothing to Disclose, Gerard Davis: Nothing to Disclose 1986 XCT + MONOCYTE-DERIVED MACROPHAGES MEDIATE LIVER FIBROSIS RESOLUTION THROUGH EFFEROCYTOSIS Kyurae Kim 1 Sung Eun Choi 1 Min Jeong Kim 1 Katherine Po Sin Chung 1 Eunmi Lee 1 Kwang Woo Lee 1 WON-IL JEONG 1 , 1 GSMSE, KAIST Background: Hepatic macrophages are key regulators of liver fibrosis progression and regression