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Salzano et al., 2019), and alpha synuclein (Park et al., 2016

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By analyzing tumor-specific receptor expression patterns through multi-omics approaches (e.g., transcriptomics, proteomics), clinicians can identify optimal targeting ligandssuch as folate for FR-overexpressing tumors or transferrin for TfR-dominant malignanciesthereby maximizing tumor-specific uptake while minimizing off-target effects [312]