bacterial and host-derived glutathione are required to activate prfa Multiple regulatory check-points control expression protein Listeria monocytogenes requires phosphotransferase systems

Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence PMC Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA: Cell Chemical Biology Listeria monocytogenes regulates PrfA activity so as to increase Download Scientific Diagram RCSB PDB 5LRS: The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30 bp operator PrfA box motif Glutathione activates virulence gene expression of an intracellular pathogen Nature Diverse roles of low molecular weight thiol GSH in Francisella's virulence, location sensing and GSH stealing from host ScienceDirect

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