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How is BPC-157 taken

Sublingual absorption delivers approximately 25 to 35% of the dose to your bloodstream, compared to approximately 80% for injection

Movement across the BBB occurs via transmembrane efflux pumps (Abbott et al., 2010) that transport molecules through endocytosis or through pores, carrier-mediated transport systems, or through direct permeation through the plasma membrane via lipophilic molecules (Banks and Kastin, 1992)

J Physiol Paris 87:313327 Sikiric P, Seiwerth S, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D (2010) Revised Roberts cytoprotection and adaptive cytoprotection and stable gastric pentadecapeptide BPC 157

Its exact mechanism of action remains partially elucidated, but evidence suggests it interacts with GABAergic, serotonergic, and hypothalamic pathways to influence central nervous system activity

Its a 15-amino-acid peptide originally derived from a protective protein naturally found in human gastric juices, and it has been studied for more than 30 years by multiple independent research groupsmost notably teams in Croatia and Taiwan