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ISSN: 10116125 Issue: 5 Pages: 195-203 Publication Title: Stereotactic and Functional Neurosurgery Volume: 85

Unlike M1 macrophages, which rely on glycolysis and a truncated TCA cycle, M2 macrophages maintain an intact TCA cycle, enhanced OXPHOS, and elevated FAO to meet their energy demands [146, 148, 150, 151]

Arriaga JM, Levy EM, Bravo AI, Bayo SM, Amat M, Aris M, Hannois A, Bruno L, Roberti MP, Loria FS, et al

NRF 2 transcriptionally induces the expression of several antioxidant defense proteins involved in iron and ROS metabolism, such as SOD1, GPX4, glutathione synthetase (GCL and GSS), HO-1, and FTH 1 (8688)

Sensors 3(8):276284 Funding This study was supported by National Institute of Health (NIH) Grants R01 EY027381, R01EY026964, and R21AI135583 awarded to AK

doi: 10.3390/ijms21030995 12 DepardieuF.BonoraM