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PPAR, peroxisome proliferators-activated receptor-

One small study found that after completing an intense resistance training workout, young men who supplemented with whey protein saw significant increases in glutathione peroxidase (enzyme activity) in comparison to a placebo group

This could explain why the activity of rhGPx3 mutant using H 2 O 2 as oxidizing substrate was in the same order of magnitude as that of human native GPx4 (34.8 U/mg) 9 and GPx4 mutant with all Cys converted to Ser (14.0 U/mg) 16 , while it was much lower than that of native GPx4 (64.6 U/mg) and the GPx4 mutant (24.6 U/mg) in the case of using PLPC-OOH as the oxidizing substrate

Whether antioxidant therapy can treat CRSwNP needs further investigation

Another study by the same authors used a similar infusion but this time with three higher intensity 45 s sprints with a fourth sprint at 130% peak oxygen consumption[26]

This finding is further supported at the cellular level by ER- on melanocytes