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AMPK: a metabolic gauge regulating whole-body energy homeostasis

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Ran Q, Gu M, Van Remmen H, Strong R, Roberts JL, Richardson A

the invention proposes the use of reduced glutathione encapsulated in a liposome (liposomal reduced glutathione) for the oral administration of a therapeutically effective amount to improve symptoms in disease states related to diminished function of the methylation pathway, and also proposes combining methylcobalamin, and/or Insulin Growth Factor 1 (IGF-1) with liposomal reduced glutathione to accomplish such improvement