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Plasma concentrations of insulin and leptin were measured using a custom developed Mesoscale (MSD) multiplex assay, which is a multi-array assay with electrochemiluminescence readout

Joustra ML, Minovic I, Janssens KAM, Bakker SJL, Rosmalen JGM

J., Jamora, C

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Additional complexity, and in accordance with IGF-1 secretion patterns, appeared when researchers found that IRS-1 was found more active in post-prandial states contrary to IRS-2 in fasting states [121]