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doi: 10.3390/ijms21207452 26 PeronRVatanabeIPManzinePRCaminsACominettiMR

Pretreatment with the GlyT1 inhibitors, sarcosine (competitive) and NFPS/ALX5407 (non-competitive), has been shown to promote neuroprotection in both ex vivo oxygenglucose deprivation (OGD) models and in vivo global cerebral ischemia models (Pinto et al

Neurotherapeutics 13 , 685701 (2016)

33,34 Because GSH is vital in detoxification and cell physiology, its depletion has been speculated to represent an important contributing factor of liver injury, and enhanced morbidity in patients with liver injury