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The lack of consensus on diagnostic criteria makes it difficult to know exactly how many people have MCS

Both layers of liposome membranes consisted of anionic phosphatidylserine (PS), where the exposed outer PS acted as an"eat-me"signal to DCs, while the inner PS interacted with the excess cationic Ca 2+ in CaP and bound to the core cGAMP complex

Finally, a meta-analysis confirmed this counterproductive effect, showing a reduced efficacy in patients undergoing combination therapy