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found no significant association between NOS3 rs1799983 polymorphism and HAPE susceptibility in Caucasians, 119 multiple studies in different geographical populations, including Japanese, 120 Chinese, 112,113 and Indian 121,122,123 populations, have highlighted a robust correlation between NOS3 rs1799983, rs199983, and rs7830 polymorphisms and HAPE risk

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These include LDL cholesterol, and triglycerides while increasing HDL cholesterol which suggests its potential benefits for for individuals with cardiovascular problems (Prete et al

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