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It could mean anything from a simple infection to something serious like kidney stones or bladder cancer

281 In the rat, The KD exacerbated disorders of glucose and lipid metabolisms and activated the renin-angiotensin-aldosterone system, 279 and the ketone body might reduce eNOS expression via NF-B singling pathway in vein endothelial cells, 280 which could collectively contribute to hypertension and endothelial dysfunction

So its hard to conclude its efficacy in weight loss

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ER stress is a critical mechanism in PD pathology, making therapeutic strategies targeting ER stress highly significant for clinical applications

the pharmaceutical composition may be administered in either one or more of ways depending on whether local or systemic treatment is of choice, and on the area to be treated