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T 3 2.5 IU/mL, will prevent disease aggravation, facilitating more effective therapeutic management

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doi: 10.1073/pnas.94.23.12533 51 ZumsteinG.FuchsR.HofmannA.Preac-MursicV.SoutschekE.WilskeB

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Activated NF-B and AP-1 inhibit collagen production and increase MMP gene transcription, leading to a decrease in collagen content in photoaged skin [151]