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[52] in a randomized, double-blind, placebo-controlled clinical trial demonstrated that acute hyperglycemia significantly impaired endothelium-dependent vasodilation in healthy subjects, whereas treatment with the RBX effectively preserved vascular responses, thereby preventing hyperglycemia-induced endothelial dysfunction

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Therefore, a typical aldehyde dehydrogenase catalytic mechanism was concluded

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Depending on what kind you take, side effects include damaging your liver, making you more likely to bleed in your gut, and slowing down your central nervous system