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Mutations in these enzymes underscore their developmental importance: Alkbh5 knockout female mice have impaired fertility owing to defective RNA metabolism in germ cells 139 , and loss-of-function mutations in FTO in mice cause growth retardation, abnormalities in brain and cardiac development, and increased perinatal lethality 140,141,142,143

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This disruption leads to blocked acetylcholine synthesis and secretion, resulting in cognitive impairments and affecting mood and memory in C57BL/6 mice (Wang L

Potential Health Benefits of GlyNAC Supplementation GlyNAC Mitochondrial Research Mitochondria, often called the "powerhouses" of cells, generate energy but can also produce harmful ROS

Nucleic Acids Res 51 , 59485980 (2023)

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