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J Amino Acids 2012:736837 Bella DL, Hirschberger LL, Kwon YH, Stipanuk MH (2002) Cysteine metabolism in periportal and perivenous hepatocytes: perivenous cells have greater capacity for glutathione production and taurine synthesis but not for cysteine catabolism

Several other groups showed that PGRMC1 enhanced chemoresistance in several cancer cells such as uterine sarcoma 43 , breast cancer 17 , endometrial tumour 13 and ovarian cancer 44,45