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Genetic factors can modulate the pathogenicity of specific bacteria, with certain pathogens being particularly capable of triggering chronic inflammation under specific genetic conditions (93)

But do not panic, these are concerns under investigation

This effect may be due to a reduction in OS [202]

Interestingly, sulforaphane, an nrf2 activator, has been shown to limit mtROS generation and prevent both NLRP3 and NLRC4 activation in murine macrophages (Samidurai et al., 2020)

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