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Adenoviral-mediated methods to overexpress sarcoplasmic-endoplasmic reticulum Ca2+/ATPase (SERCA) have shown promise in preclinical and early-phase clinical trials

In the placebo group, significantly positive correlations were observed between oxidative stress detected by the FR method (r=0.88, P=0.008) and GST activity, as well as between oxidative stress detected by the FR method (r= 0.86, P= 0.01) and SOD activity

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[202] have reported a zero-valent-iron nanoparticle (ZVI-NP), which could inactivate NRF2-mediated cytoprotective program

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