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Stewart, J

Clinical trials indicate that SAMe administration enhances glutathione production in hepatic tissue and red blood cells

In this review, we summarize the current landscape of hiPSC-derived cardiac model systems, critically evaluate their applications in preclinical drug development, and discuss persistent challenges, including tissue maturation, scalability, reproducibility, and regulatory validation of these models

doi: 10.1096/fj.202201400R 29

Additionally, peroxynitrite impedes T cell migration by nitrating TCRs, which hinders the binding of epitope-specific amino acids to MHC molecules on tumor cells [27]

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