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The protocol should have a defined review point, typically at the end of the AOD-9604 cycle, where the response is assessed

Structure determination was initially performed by molecular replacement in Phaser 28 using a search model generated by Alphafold2 25

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For instance, a study reported no significant association between C677T and bipolar disorder 64 , while another study found no evidence for C677T genotypic or allelic association with BD regardless of type I or II 65

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